Constitutive Modelling of Failing Myocardium

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Auckland Bioengineering Institute

70 Symonds Street

Lecture Theatre G10

Auckland, Auckland 1010

New Zealand

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Event description
Structurally based constitutive modeling provides an approach to improve understanding of the structure-function relationship in myocardium.

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Most constitutive models of passive myocardium are formulated based on phenomenological approaches. Although such constitutive models can reproduce aspects of the biomechanical behaviour of myocardium, they generally do not reflect the microstructural and material changes that occur as myocardium progressively remodels during growth or disease.

In this talk, Abdallah will present a novel structurally motivated constitutive model of passive myocardium that directly links quantitative characteristics of myocardial collagen organisation to the mechanical function of the heart. As such, it provides insight into the biophysical relationship between structure and function of the myocardium that can be used to inform the development of more effective treatments for heart failure.

Abdallah Hasaballa obtained his Master degree in Engineering Science from the University of Malaya in 2014 and his PhD degree from the University of Auckland in 2020. He is now a post-doctoral researcher in the ABI. He is currently developing a novel model-based analysis of cardiac medical images to determine the biophysical mechanisms responsible for impaired mechanical function during heart failure.

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Auckland Bioengineering Institute

70 Symonds Street

Lecture Theatre G10

Auckland, Auckland 1010

New Zealand

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